1. Self-curing methyl methacrylate causes no more tissue reaction than does Vitallium in the rabbit or monkey.
2. It is not strong enough to be used without reinforcement where there is transverse stress. The strength seems adequate to withstand most compression stresses in the body. Strength is a limiting factor, however.
3. It can be obtained sterile and is available in convenient packages which can be stored for long periods.
4. Heat of polymerization is, at present, a troublesome and limiting factor. It can be controlled by various methods, but this adds to the inconvenience of using the material.
5. It can be molded quickly and easily by use of a negative mold.
6. It will not remain absolutely tight against the bone. This applies not only to plastic but also to steel and Vitallium.
7. Although at the present time, no uses in orthopaedic surgery can be recommended unequivocally, it is believed that it may find a place following more research on the basic material, especially as rgards the heat of polymerization.