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Unusual Manifestations of Chordoma A REPORT OF TWO CASES
JAMES E. FOX; JOHN G. BATSAKIS; LUIS R. OWANO
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From the Department of Pathology, University of Michigan Medical Center, Ann Arbor, and The Swedish-American Hospital, Rockford, Illinois
1968 by The Journal of Bone and Joint Surgery, Incorporated
The Journal of Bone & Joint Surgery.  1968; 50:1618-1628 
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Abstract

Unusual behavior in two cases of chordoma are reported. The first is a sacral primary tumor with widespread metastases. Review of the literature indicates that

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well documented instances of metastases from these neoplasms are an uncommon occurrence; and that in the majority of cases the sacral area is the primary site. The second report is of a vertebral chordoma that underwent sarcomatous histological transformation three and one-half years after radiation therapy. This is apparently a previously unreported phenomenon.

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    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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