A prospective study was done to evaluate the efficacy of treatment with
1,000 rads of radiation in the prevention of heterotopic ossification after
total hip arthroplasty in patients who are at high risk. In a previous
prospective study, patients who were at high risk for heterotopic
ossification after total hip arthroplasty were identified and an effective
regimen for its prevention was established. It was demonstrated that
treatment with 2,000 rads of radiation that was initiated within four days
after the total hip arthroplasty was highly effective in the prevention of
heterotopic ossification and in the prevention of recurrence after
resection of existing ossification. In the present study, 1,000 rads of
radiation was administered in increments of 200 rads over a period of five
to seven days and was as effective as treatment with 2,000 rads. The
protocol of 1,000 rads is preferable because it reduces the risk of
malignancy and the duration of hospitalization.