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Scientific Article   |    
Shoulder Arthroplasty for Osteoarthritis Secondary to Glenoid Dysplasia
John W. Sperling, MD; Robert H. Cofield, MD; Scott P. Steinmann, MD
View Disclosures and Other Information
Investigation performed at the Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota

Robert H. Cofield, MD
Scott P. Steinmann, MD
Department of Orthopedic Surgery, Mayo Clinic, 200 First Street S.W., Rochester, MN 55902. E-mail address for J.W. Sperling: sperling.john@mayo.edu

The authors did not receive grants or outside funding in support of their research or preparation of this manuscript. They did not receive payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. Commercial entities (Mayo Foundation and Smith and Nephew) paid or directed, or agreed to pay or direct, benefits to a research fund, foundation, educational institution, or other charitable or nonprofit organization with which the authors are affiliated or associated.

The Journal of Bone & Joint Surgery.  2002; 84:541-546 
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Abstract

Background: Between 1980 and 1997, six patients (seven shoulders) with glenoid dysplasia and osteoarthritis underwent shoulder arthroplasty at our institution because of moderate or severe shoulder pain. There were four hemiarthroplasties and three total shoulder arthroplasties.

Methods: All six patients (seven shoulders) were followed for a minimum of two years or until the time of revision surgery. The average duration of follow-up was 7.3 years (range, 1.3 to sixteen years).

Results: One shoulder treated with total shoulder arthroplasty underwent revision surgery because of infection and loosening of the glenoid component 5.8 years following the arthroplasty. Three shoulders treated with hemiarthroplasty underwent revision to total shoulder arthroplasty as a result of glenoid arthrosis at sixteen months, twenty months, and thirty-four months. In each of these shoulders, glenoid deficiency and cartilage loss were not addressed at the time of the original hemiarthroplasty. The one shoulder that did not undergo revision after hemiarthroplasty had a glenoid osteotomy performed at the time of the hemiarthroplasty.

Conclusions: The data from this study suggest that glenoid deficiency and cartilage wear should be addressed in some way at the time of shoulder arthroplasty in patients with glenoid dysplasia.

Figures in this Article
    Glenoid dysplasia is a rare shoulder disorder that was first described in the literature by Valentine in 1931 1,2 . Although there have been a few reports of early development of osteoarthritis in patients with glenoid dysplasia 3,4 , currently we are not aware of any information regarding the influence of glenoid deficiency on the results of shoulder arthroplasty in patients with this disorder. The purpose of our study was to determine the outcomes of patients with glenoid dysplasia who underwent shoulder arthroplasty.
     
    Anchor for JumpAnchor for Jump
    +Fig. 1-A:Figs. 1-A through 1-F Case 6. A forty-year-old man with moderate dysplasia underwent hemiarthroplasty. Figs. 1-A and 1-B These anteroposterior and axillary radiographs demonstrate posterior and inferior deficiency of the glenoid.
     
    Anchor for JumpAnchor for Jump
    +Fig. 1-B:Figs. 1-A through 1-F Case 6. A forty-year-old man with moderate dysplasia underwent hemiarthroplasty. Figs. 1-A and 1-B These anteroposterior and axillary radiographs demonstrate posterior and inferior deficiency of the glenoid.
     
    Anchor for JumpAnchor for Jump
    +Fig. 1-C:Figs 1-C and 1-D Radiographs made twenty months following surgery demonstrate glenoid arthrosis and superior subluxation of the humeral head.
     
    Anchor for JumpAnchor for Jump
    +Fig. 1-D:Figs 1-C and 1-D Radiographs made twenty months following surgery demonstrate glenoid arthrosis and superior subluxation of the humeral head.
     
    Anchor for JumpAnchor for Jump
    +Fig. 1-E:Figs. 1- E and 1-F The patient underwent revision to total shoulder arthroplasty with bone-grafting and implantation of a glenoid component.
     
    Anchor for JumpAnchor for Jump
    +Fig. 1-F:Figs. 1- E and 1-F The patient underwent revision to total shoulder arthroplasty with bone-grafting and implantation of a glenoid component.
     
    Anchor for JumpAnchor for JumpTABLE I:  Results
    *Pain was graded on a scale of 1 (no pain) through 5 (severe pain), as previously described by Neer et al. 6 and by Cofield 7 . A modified Neer result-rating system was used 8 .
    CaseAge (yr)Type of Shoulder ArthroplastyRevisionDuration of Follow- up (mo)Elevation (deg)External Rotation (deg)Pain* (points)Result Rating
    Preop. Postop. Preop. Postop.Preop. Postop.
    159TotalNo141120155254551Excellent
    260TotalNo139100170  06051Excellent
    360TotalYes  70120140503551Unsatisfactory
    446HemiYes  34  8018030  055Unsatisfactory
    553HemiYes  16115115407554Unsatisfactory
    640HemiYes  20110100607044Unsatisfactory
    739HemiNo197  90180206052Excellent
    Between 1980 and 1997, six patients (seven shoulders) with glenoid dysplasia and osteoarthritis were treated with shoulder arthroplasty at our institution because of moderate or severe shoulder pain that failed to respond satisfactorily to nonoperative management. Four hemiarthroplasties and three total shoulder arthroplasties were performed. One patient underwent bilateral total shoulder arthroplasty. All seven shoulders with complete preoperative evaluation and operative records that had been followed for a minimum of two years or until the time of revision surgery were included in the study. The average duration of follow-up was 7.3 years (range, 1.3 to sixteen years). Four shoulders required revision surgery: one, at sixteen months; one, at twenty months; one, at thirty-four months; and one, at 5.8 years. Each of the remaining three shoulders was followed for at least ten years.
    The diagnosis was based on preoperative radiographic findings that were consistent with glenoid dysplasia 1,4,5 . Additionally, the diagnosis was confirmed at the time of surgery. All of the patients were men, and their ages ranged from thirty-nine to sixty years (average, fifty-one years). One patient underwent arthroscopic d�bridement of a labral tear three years prior to the shoulder arthroplasty. The remaining six shoulders had no history of surgery.

    Clinical Review

    Pain was graded on a scale of 1 through 5, as previously described by Neer et al. 6 and by Cofield 7 : 1 point was assigned when there was no pain; 2 points were assigned for slight pain; 3 points, for pain after unusual activities; 4 points, for moderate pain; and 5 points, for severe pain. Active elevation and external rotation were recorded in degrees, and internal rotation was graded according to the posterior spinal region that the thumb could reach actively.

    Radiographic Review

    The radiographs of the patients who had had a hemiarthroplasty were reviewed to determine the presence or absence of glenohumeral subluxation, periprosthetic radiolucency, subsidence or a shift in the position of the humeral component, loss of glenoid cartilage, and erosion of the glenoid. The amount of glenoid erosion, which was determined in relation to the anterior subchondral plate, was graded as mild (<5 mm), moderate (5 to 10 mm), or severe (>10 mm). The radiographs of the patients who had had a total shoulder arthroplasty were reviewed to determine the presence or absence of glenohumeral subluxation, periprosthetic radiolucency, subsidence or a shift in the position of the humeral component, and migration or tilt of the glenoid component.
    Periprosthetic lucency was classified as grade 0 when there was no radiolucent line, grade 1 when the line was &le;1 mm wide and incomplete, grade 2 when the line was 1 mm wide and complete, grade 3 when the line was 1.5 mm wide and incomplete, grade 4 when the line was 1.5 mm wide and complete, and grade 5 when the line was 2 mm wide and complete. Glenohumeral subluxation was evaluated with regard to its direction and the amount of translation of the center of the prosthetic head relative to the center of the glenoid or the glenoid component. It was recorded as none, mild when there was <25% translation, moderate when there was 25% to 50% translation, and severe when there was >50% translation. Migration or tilt of the glenoid component was recorded as either present or absent, as was subsidence or shift of the humeral component.

    Operative Technique

    Following implantation of the trial humeral component, the glenoid was inspected. Three shoulders with degenerative changes of the glenoid articular surface underwent total shoulder arthroplasty. Two of the glenoid components-an all-polyethylene Neer component and a metal-backed Neer component-were implanted with cement. A Cofield tissue-ingrowth glenoid component was placed in the third shoulder. One shoulder underwent bone-grafting of the posterior aspect of the glenoid with bone obtained from the humeral head. Another shoulder underwent z-lengthening of the subscapularis.
    Four shoulders underwent hemiarthr7oplasty, and, in one of them, a glenoid osteotomy was performed from a posterior approach. In all four shoulders, at least one-half of the glenoid articular cartilage was noted to be completely worn, exposing subchondral bone.

    Revisions

    Four shoulders, three originally treated with hemiarthroplasty and one originally treated with total shoulder arthroplasty, underwent revision surgery. All three revisions of the hemiarthroplasties were performed because of pain associated with glenoid arthrosis. Of the shoulders originally treated with hemiarthroplasty, one underwent revision to total shoulder arthroplasty with glenoid bone-grafting and placement of a glenoid component twenty months following the hemiarthroplasty ( Figs. 1-A , 1-B , 1-C , 1-D , 1-E , and 1-F ). Another underwent revision to total shoulder arthroplasty with placement of a glenoid component and exchange of the humeral head sixteen months following the hemiarthroplasty. The third shoulder underwent revision to bipolar arthroplasty at another institution thirty-four months following the hemiarthroplasty. The patient originally treated with total shoulder arthroplasty underwent component removal because of a suspected Pseudomonas infection (positive preoperative aspirate) and a loose glenoid component 5.8 years following the total shoulder arthroplasty. All cultures of intraoperative specimens were negative. The patient underwent reimplantation of a hemiarthroplasty component two months following resection.

    Pain

    All shoulders had moderate or severe pain prior to surgery. Three shoulders with glenoid arthrosis had moderate or severe pain after hemiarthroplasty. Each of these shoulders underwent revision surgery. The remaining four shoulders had no or slight pain.

    Range of Motion

    Result Rating

    The total shoulder arthroplasties were followed by two excellent results and one unsatisfactory result. The hemiarthroplasties were followed by one excellent result and three unsatisfactory results.

    Radiographic Analysis

    Total Shoulder Arthroplasty

    Preoperative radiographs were available for two of the three shoulders that underwent total shoulder arthroplasty. Both shoulders had moderate glenoid hypoplasia according to the scale of Wirth et al. 4 , and one of them had mild posterior and superior subluxation preoperatively.
    The most recent follow-up radiographs showed no periprosthetic lucency adjacent to any of the three humeral components, but there was a radiolucent line adjacent to each of the three glenoid components. The metal-backed Neer glenoid component was surrounded by a 1.5-mm complete lucent line, and there was a shift in component position consistent with loosening of the component. There was a complete lucent line of >2 mm around the all-polyethylene Neer component, which had also shifted in a manner consistent with loosening. There was a 1-mm incomplete lucent line adjacent to the Cofield tissue-ingrowth component, which had not shifted in position. At the most recent follow-up evaluation, one shoulder had mild posterior and superior subluxation.

    Hemiarthroplasty

    Of the four shoulders that underwent hemiarthroplasty, one had had moderate preoperative hypoplasia and three had had severe preoperative hypoplasia according to the scale of Wirth et al. 4 . Preoperatively, three shoulders had had subluxation: moderate posterior and mild superior subluxation had been noted in two of these shoulders, and mild posterior and superior subluxation had been noted in one. There was wear of the glenoid cartilage in all four shoulders.
    At the most recent follow-up evaluation, glenohumeral subluxation was present in all four shoulders: mild posterior and superior subluxation was seen in two shoulders; moderate posterior subluxation, in one; and moderate posterior and mild superior subluxation, in one. There was a 1.5-mm incomplete radiolucent line adjacent to two humeral components, without shift or subsidence of either component. There was glenoid bone erosion in three shoulders: it was mild in two and moderate in one.
    Glenoid dysplasia is a developmental anomaly of the scapula that is characterized by incomplete ossification of the inferior aspect of the glenoid and the scapular neck 9 . Glenoid dysplasia has also been termed "glenoid hypoplasia" and "dentated glenoid." 1 Ossification of the glenoid fossa occurs through two separate ossification centers in normal shoulder development10. The first ossification center appears around the tenth year and closes by the fifteenth year, and it originates in the superior aspect of the glenoid fossa, at the base of the coracoid 10 . The ossification center of the inferior aspect of the glenoid fossa appears around puberty10. Glenoid dysplasia is thought to result from a failure of development of the inferior aspect of the apophysis1.
    Typically, radiographic findings include dysplasia of the neck of the scapula with an irregular articular surface of the glenoid 1,5 . Associated findings may include dysplasia of the humeral head, dysplasia of the coracoid, and hooking of the lateral part of the clavicle3. Additionally, the acromion may be elongated and inferiorly directed 4 . Patients with glenoid dysplasia typically have symptoms in adolescence or in the fifth and sixth decades of life, and this condition has been reported more frequently in men11.
    We are not aware of any prior reports addressing the management of glenoid dysplasia in the setting of shoulder arthroplasty. To our knowledge, the largest report on glenoid hypoplasia in the orthopaedic literature is by Wirth et al.4. In their study of sixteen patients, two had glenohumeral degenerative joint disease. Neither of these patients underwent surgery. The authors noted that hemiarthroplasty "may play a role in the rare patient who has unremitting symptoms and moderate or severe degenerative changes of the shoulder joint." 4
    The management of these patients requires a thorough preoperative examination that includes careful evaluation of the preoperative radiographs. Determination of the severity of the glenoid dysplasia preoperatively will facilitate adequate preparation for surgery. Preoperative computed tomography scanning with or without three-dimensional reconstruction, although not used for the patients in this study, may improve the ability to determine the degree of glenoid bone deficiency.
    In the current study, posterior deficiency occurred in conjunction with inferior deficiency. The radiographs demonstrated frank deficiency of bone formation in the posterior region rather than the usual pattern of posterior wear seen in osteoarthritis. Additionally, at the time of surgery, the deficiency of inferior and posterior bone was in contrast to the usual appearance of posterior wear alone that is typically seen in osteoarthritis.
    The data from this study suggest that glenoid deficiency and cartilage wear should be addressed at the time of shoulder arthroplasty in patients with glenoid dysplasia. Currently, there are three options for the treatment of the inferior and posterior bone deficiency. First, one can consider bone-grafting the deficient region in conjunction with placement of a glenoid component 12 . Second, one can consider bone-grafting or osteotomy alone in conjunction with a hemiarthroplasty. Finally, one can accommodate the deficient inferior-posterior region with a glenoid component that substitutes metal for the deficient bone.
    Hemiarthroplasty alone appears to be an unsatisfactory option for the treatment of this disease process. Three of the four hemiarthroplasties in our series had to be revised because of glenoid arthrosis. Radiographic review demonstrated that these three shoulders had substantial inferior and posterior glenoid deficiency that had not been corrected at the time of the primary arthroplasty. The one shoulder that did not require revision surgery after hemiarthroplasty had a glenoid osteotomy performed at the time of the hemiarthroplasty.
    Trout TE,Resnick D. Glenoid hypoplasia and its relationship to instability. Skeletal Radiol,1996;25: 37-40.. 2537  1996  [PubMed]
     
    Valentine B. Die kongenitale schulterluxation. Orthop Chir,1931;55: 229.. 55229  1931 
     
    Resnick D, Walter RD,Crudale AS. Bilateral dysplasia of the scapular neck. AJR Am J Roentgenol,1982;139: 387-9.. 139387  1982  [PubMed]
     
    Wirth MA, Lyons FR,Rockwood CA Jr. Hypoplasia of the glenoid. A review of sixteen patients. J Bone Joint Surg Am,1993;75: 1175-84.. 751175  1993  [PubMed]
     
    Pettersson H. Bilateral dysplasia of the neck of scapula and associated anomalies. Acta Radiol Diagn (Stockh),1981;22: 81-4.. 2281  1981  [PubMed]
     
    Neer CS 2nd, Watson KC,Stanton FJ. Recent experience in total shoulder replacement. J Bone Joint Surg Am,1982;64: 319-37.. 64319  1982  [PubMed]
     
    Cofield RH. Total shoulder arthroplasty with the Neer prosthesis. J Bone Joint Surg Am,1984;66: 899-906.. 66899  1984  [PubMed]
     
    Sperling JW, Cofield RH,Rowland CM. Neer hemiarthroplasty and Neer total shoulder arthroplasty in patients fifty years old or less. Long-term results. J Bone Joint Surg Am,1998;80: 464-73.. 80464  1998  [PubMed]
     
    Currarino G, Sheffield E,Twickler D. Congenital glenoid dysplasia. Pediatr Radiol,1998;28: 30-7.. 2830  1998  [PubMed]
     
    Stanciu C,Morin B. Congenital glenoid dysplasia: case report in two consecutive generations. J Pediatr Orthop,1994;14: 389-91.. 14389  1994  [PubMed]
     
    Lintner DM, Sebastianelli WJ, Hanks GA,Kalenak A. Glenoid dysplasia. A case report and review of the literature. Clin Orthop,1992;283: 145-8.. 283145  1992  [PubMed]
     
    Steinmann SP,Cofield RH. Bone grafting for glenoid deficiency in total shoulder replacement. J Shoulder Elbow Surg,2000;9: 361-7.. 9361  2000  [PubMed]
     

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    Anchor for JumpAnchor for Jump
    +Fig. 1-A:Figs. 1-A through 1-F Case 6. A forty-year-old man with moderate dysplasia underwent hemiarthroplasty. Figs. 1-A and 1-B These anteroposterior and axillary radiographs demonstrate posterior and inferior deficiency of the glenoid.
    Anchor for JumpAnchor for Jump
    +Fig. 1-B:Figs. 1-A through 1-F Case 6. A forty-year-old man with moderate dysplasia underwent hemiarthroplasty. Figs. 1-A and 1-B These anteroposterior and axillary radiographs demonstrate posterior and inferior deficiency of the glenoid.
    Anchor for JumpAnchor for Jump
    +Fig. 1-C:Figs 1-C and 1-D Radiographs made twenty months following surgery demonstrate glenoid arthrosis and superior subluxation of the humeral head.
    Anchor for JumpAnchor for Jump
    +Fig. 1-D:Figs 1-C and 1-D Radiographs made twenty months following surgery demonstrate glenoid arthrosis and superior subluxation of the humeral head.
    Anchor for JumpAnchor for Jump
    +Fig. 1-E:Figs. 1- E and 1-F The patient underwent revision to total shoulder arthroplasty with bone-grafting and implantation of a glenoid component.
    Anchor for JumpAnchor for Jump
    +Fig. 1-F:Figs. 1- E and 1-F The patient underwent revision to total shoulder arthroplasty with bone-grafting and implantation of a glenoid component.
    Anchor for JumpAnchor for JumpTABLE I:  Results
    *Pain was graded on a scale of 1 (no pain) through 5 (severe pain), as previously described by Neer et al. 6 and by Cofield 7 . A modified Neer result-rating system was used 8 .
    CaseAge (yr)Type of Shoulder ArthroplastyRevisionDuration of Follow- up (mo)Elevation (deg)External Rotation (deg)Pain* (points)Result Rating
    Preop. Postop. Preop. Postop.Preop. Postop.
    159TotalNo141120155254551Excellent
    260TotalNo139100170  06051Excellent
    360TotalYes  70120140503551Unsatisfactory
    446HemiYes  34  8018030  055Unsatisfactory
    553HemiYes  16115115407554Unsatisfactory
    640HemiYes  20110100607044Unsatisfactory
    739HemiNo197  90180206052Excellent
    Trout TE,Resnick D. Glenoid hypoplasia and its relationship to instability. Skeletal Radiol,1996;25: 37-40.. 2537  1996  [PubMed]
     
    Valentine B. Die kongenitale schulterluxation. Orthop Chir,1931;55: 229.. 55229  1931 
     
    Resnick D, Walter RD,Crudale AS. Bilateral dysplasia of the scapular neck. AJR Am J Roentgenol,1982;139: 387-9.. 139387  1982  [PubMed]
     
    Wirth MA, Lyons FR,Rockwood CA Jr. Hypoplasia of the glenoid. A review of sixteen patients. J Bone Joint Surg Am,1993;75: 1175-84.. 751175  1993  [PubMed]
     
    Pettersson H. Bilateral dysplasia of the neck of scapula and associated anomalies. Acta Radiol Diagn (Stockh),1981;22: 81-4.. 2281  1981  [PubMed]
     
    Neer CS 2nd, Watson KC,Stanton FJ. Recent experience in total shoulder replacement. J Bone Joint Surg Am,1982;64: 319-37.. 64319  1982  [PubMed]
     
    Cofield RH. Total shoulder arthroplasty with the Neer prosthesis. J Bone Joint Surg Am,1984;66: 899-906.. 66899  1984  [PubMed]
     
    Sperling JW, Cofield RH,Rowland CM. Neer hemiarthroplasty and Neer total shoulder arthroplasty in patients fifty years old or less. Long-term results. J Bone Joint Surg Am,1998;80: 464-73.. 80464  1998  [PubMed]
     
    Currarino G, Sheffield E,Twickler D. Congenital glenoid dysplasia. Pediatr Radiol,1998;28: 30-7.. 2830  1998  [PubMed]
     
    Stanciu C,Morin B. Congenital glenoid dysplasia: case report in two consecutive generations. J Pediatr Orthop,1994;14: 389-91.. 14389  1994  [PubMed]
     
    Lintner DM, Sebastianelli WJ, Hanks GA,Kalenak A. Glenoid dysplasia. A case report and review of the literature. Clin Orthop,1992;283: 145-8.. 283145  1992  [PubMed]
     
    Steinmann SP,Cofield RH. Bone grafting for glenoid deficiency in total shoulder replacement. J Shoulder Elbow Surg,2000;9: 361-7.. 9361  2000  [PubMed]
     
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