Extract
Cross-linking changes the wear and mechanical behavior of ultra-high
molecular weight polyethylene. Contemporary highly cross-linked ultra-high
molecular weight polyethylene has demonstrated markedly improved wear in vitro
and a reduction in static and fatigue strength compared with conventional
ultra-high molecular weight
polyethylene1-7.Studies employing hip simulators have shown a reduction in the volume of
wear debris generated with cross-linked polyethylene in comparison with that
generated with conventional
polyethylene8.
However, the average size of wear particles also appeared to be reduced, which
means that the actual number of generated particles may not be
decreased8. The
osteolytic response to particulate debris is variable and may depend more on a
number of factors, including the number and the size of particles, than on the
total volume of debris
generated9,10.
The long-term clinical results of the use of currently available contemporary
highly cross-linked ultra-high molecular weight polyethylene components in
total hip arthroplasty are not yet known.