Extract
As a result of medical complexity and urgent care needs, the trauma patient
population has not been considered conducive to study with use of traditional
clinical trial designs. Efforts to enhance the scientific rigor of clinical
research in musculoskeletal trauma have highlighted several key outstanding
needs that have not been met by most clinical studies to date. Large
multicenter trials, international trials, large cohort outcome studies, and
cost-benefit analyses are generally lacking in the orthopaedic trauma
literature. There is an opportunity for clinical trials to produce broadly
accepted treatment protocols.