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Autologous Chondrocyte Implantation in the Knee Joint: Open Compared with Arthroscopic TechniqueComparison at a Minimum Follow-up of Five Years
Alberto Ferruzzi, MD1; Roberto Buda, MD1; Cesare Faldini, MD1; Francesca Vannini, MD1; Francesco Di Caprio, MD1; Deianira Luciani, MD1; Sandro Giannini, MD1
1 Department of Orthopaedic Surgery, University of Bologna, Istituto Ortopedico Rizzoli, Via G.C. Pupilli 1, Bologna 40136, Italy
The Journal of Bone & Joint Surgery.  2008; 90:90-101  doi:10.2106/JBJS.H.00633
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Extract

Autologous chondrocyte implantation is a widely used technique for treating cartilage lesions1-10. The technique, first introduced and described by Brittberg et al. in 199411, required an arthrotomy of the joint, débridement of the lesions, and the suturing of a periosteal flap to create a pocket to host the chondrocytes. Autologous chondrocyte implantation in the knee joint has provided hyaline-like repair tissue11-16, with satisfactory clinical results in 80% to 90% of patients1,7,17. Moreover, autologous chondrocyte implantation has been shown to be a valid alternative to the mosaicplasty and microfracture repair techniques used in the treatment of osteochondral lesions of the knee1,6,13,17-20.
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    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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