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Unusual Presentation of Lipoblastoma as a Skin Dimple of the ThighA Report of Three Cases
Kevin B. Jones, MD1; José A. Morcuende, MD, PhD1; Barry R. DeYoung, MD1; Georges Y. El-Khoury, MD1; Joseph A. Buckwalter, MD, MS1; Frederick R. Dietz, MD1
1 Departments of Orthopaedic Surgery (K.B.J., J.A.M., J.A.B., F.R.D.), Surgical Pathology (B.R.D.), and Musculoskeletal Radiology (G.Y.El-K.), University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242. E-mail address for F.R. Dietz: frederick-dietz@uiowa.edu
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The authors did not receive grants or outside funding in support of their research or preparation of this manuscript. They did not receive payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the authors are affiliated or associated.
Investigation performed at the Departments of Orthopaedic Surgery, Surgical Pathology, and Musculoskeletal Radiology, University of Iowa Hospitals and Clinics, Iowa City, Iowa

The Journal of Bone and Joint Surgery, Incorporated
J Bone Joint Surg Am, 2004 May 01;86(5):1040-1046
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The term lipoblastoma was first used by Jaffé in 19261 to refer to a tumor of immature fat cells. It was not consistently applied to the benign embryonal adipose tumors that now bear its name until Chung and Enzinger established the initial morphological criteria for its diagnosis in 19732. In doing so, they expanded on the descriptions provided by Vellios et al. in 19583 and by Shear in 19674 in their reports on the diffuse form of the tumor, called lipoblastomatosis. Despite their infrequent occurrence in the overall population and their rare discussion in the literature, lipoblastoma and lipoblastomatosis represent >15% of all benign soft-tissue neoplasms that present in the extremities of children who are five years of age or less5. The typical—almost exclusive—presentation of lipoblastoma as described in the literature is that of a painless soft-tissue mass, with or without progressive enlargement and with or without mass-effect symptoms when located near vital structures.
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    thigh ; lipoblastoma

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