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Bilateral Exercise-Induced Compartment Syndrome of the Thigh and Leg Associated with Massive Heterotopic OssificationA Case Report
Joseph R. Lynch, MD1; Matthew V. Jenkins, BS1; Douglas G. Smith, MD1; Carlo Bellabarba, MD1
1 Department of Orthopaedics and Sports Medicine, Harborview Medical Center, University of Washington School of Medicine, 325 Ninth Avenue, Box 359798, Seattle, WA 98104. E-mail address for J.R. Lynch: joelynch@u.washington.edu
View Disclosures and Other Information
The authors did not receive grants or outside funding in support of their research for or preparation of this manuscript. They did not receive payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the authors are affiliated or associated.
Investigation performed at the Department of Orthopaedics and Sports Medicine, Harborview Medical Center, University of Washington School of Medicine, Seattle, Washington

The Journal of Bone and Joint Surgery, Incorporated
J Bone Joint Surg Am, 2006 Oct 01;88(10):2265-2269. doi: 10.2106/JBJS.E.01441
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Compartment syndrome of the thigh is an infrequent phenomenon, and it is even more rare for it to occur as a result of exercise. The vast majority of cases are associated with femoral fractures, thigh contusions, prolonged compression, and/or vascular injuries1,2. A search of the English-language literature revealed only eleven cases caused by intense or prolonged exercise (Table I). More importantly, we found only one reported case of bilateral thigh and leg compartment syndrome, the outcome of which was death secondary to multiorgan failure3. We are presenting what we believe is the first report on a survivor of exercise-induced compartment syndrome of both thighs and legs. Follow-up at fourteen months demonstrated reasonable functional recovery despite life-threatening medical complications and the development of massive heterotopic ossification.
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