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Selected Instructional Course Lecture   |    
Allografts in Articular Cartilage Repair
Simon Görtz, MD1; William D. Bugbee, MD1
1 Department of Orthopaedic Surgery, University of California, San Diego, 4150 Regents Park Row, Suite 300, La Jolla, CA 92037. E-mail address for W.D. Bugbee: wbugbee@ucsd.edu
View Disclosures and Other Information
The authors did not receive grants or outside funding in support of their research for or preparation of this manuscript. They did not receive payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the authors are affiliated or associated.
Printed with permission of the American Academy of Orthopaedic Surgeons. This article, as well as other lectures presented at the Academy's Annual Meeting, will be available in February 2007 in Instructional Course Lecturs, Volume 56. The complete volume can be ordered online at www.aaos.org, or by calling 800-626-6726 (8 a.m.-5 p.m., Central time).
An Instructional Course Lecture, American Academy of Orthopaedic Surgeons

The Journal of Bone and Joint Surgery, Incorporated
J Bone Joint Surg Am, 2006 Jun 01;88(6):1374-1384
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Extract

The use of osteochondral transplants in biologic reconstruction of the knee joint has an extensive clinical history, dating back to Erich Lexer's pioneering work in the early twentieth century1. Transplantation of small-fragment fresh allografts evolved into a routine procedure of choice at certain institutions in North America in the 1970s2-4 and has since undergone a renaissance as a result of renewed clinical interest and scientific investigation. Subsequently, refinements in transplantation protocols, increased availability of fresh donor tissue, as well as physician and patient demand have driven an emerging trend toward biologic resurfacing as an alternative to prosthetic joint replacement and restoration in a select patient population. Although there are several reparative and restorative options for cartilage replacement5-9, osteochondral allografting remains the only biomimetic technique (emulating normal biology) that restores architecturally appropriate, mature hyaline cartilage
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    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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