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BIOPHYSICAL AND PHYSIOLOGICAL INVESTIGATIONS ON CARTILAGE AND OTHER MESENCHYMAL TISSUES II. The Ultrastructure of Bovine and Human Nuclei Pulposi
BENGT SYLVÉN; STEN PAULSON; CARL HIRSCH; OLLE SNELLMAN
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STOCKHOLM AND UPSALA, SWEDEN
1951 by The American Orthopaedic Association, Inc.
J Bone Joint Surg Am, 1951 Apr 01;33(2):333-340
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Abstract

Electron microscopy of healthy nuclei pulposi indicates that the intercellular matrix should be regarded as a three-dimensional lattice gel system, containing a dense network of poorly differentiated collagenous fibrils and an amorphous interfibrillar substance. During aging, this system becomes subject to an irregular disappearance of the amorphous mucoid material, whereby the fibrils become partly unmasked. The mucoid interfibrillar material is probably responsible for the high water content and water-binding capacity.

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    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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