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Osteogenic Sarcoma A Follow-up Study of the Ninety-Four Cases Observed at the Massachusetts General Hospital from 1920 to 1960
Marvin S. Weinfeld; H. Robert DudleyJR.
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Orthopaedic Surgical Service and the James Homer Wright Pathology Laboratories of the Massachusetts General Hospital and the Department of Pathology, Harvard Medical School, Boston
1962 by The Journal of Bone and Joint Surgery, Incorporated
J Bone Joint Surg Am, 1962 Mar 01;44(2):269-276
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All cases of osteogenic sarcoma treated at the Massachusetts General Hospital during the forty-year period 1920 to 1960 were studied. Ninety-four patients fulfilled the diagnostic criteria of this study, and follow-up imiformation was obtained in ninety-two of the cases. Thirteen patients survived more than five years after surgical therapy.

The majority of the tumors were located imi the metaphyses of the bones having the greatest growth activity; that is, forty in the distal part of the femur, fourteen in the proximal part of the tibia, and ten in the proximal part of the humerus.

The tumors occurred most frequently during the period of active growth, forty-nine occurring in patients between the ages of fifteen and twenty-four years. Paget's disease was associated with osteogenic sarcoma in eleven patients, all of whom were over the age of forty.

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    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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