Evidence-Based Orthopaedics   |    
Single Mini-Incision Total Hip Replacement for the Management of Arthritic Disease of the HipA Systematic Review and Meta-Analysis of Randomized Controlled Trials
Mari Imamura, PhD1; Niall A. Munro, MD, FRCS(Tr&Orth)2; Shihua Zhu, PhD1; Cathryn Glazener, PhD1; Cynthia Fraser, MA1; James Hutchison, FRCSEd, PhD3; Luke Vale, PhD1
1 Health Services Research Unit, University of Aberdeen, Health Sciences Building, Foresterhill, Aberdeen AB25 2ZD, United Kingdom. E-mail address for M. Imamura: m.imamura@abdn.ac.uk
2 Golden Jubilee National Hospital, Agamemnon Street, Clydebank G81 4DY, United Kingdom
3 Department of Orthopaedics, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, United Kingdom
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Investigation performed at the Health Services Research Unit, University of Aberdeen, Aberdeen, United Kingdom

Disclosure: One or more of the authors received payments or services, either directly or indirectly (i.e., via his or her institution), from a third party in support of an aspect of this work. In addition, one or more of the authors, or his or her institution, has had a financial relationship, in the thirty-six months prior to submission of this work, with an entity in the biomedical arena that could be perceived to influence or have the potential to influence what is written in this work. No author has had any other relationships, or has engaged in any other activities, that could be perceived to influence or have the potential to influence what is written in this work. The complete Disclosures of Potential Conflicts of Interest submitted by authors are always provided with the online version of the article.

Copyright © 2012 by The Journal of Bone and Joint Surgery, Inc.
J Bone Joint Surg Am, 2012 Oct 17;94(20):1897-1905. doi: 10.2106/JBJS.K.00495
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Mini-incision total hip replacement continues the current trend in orthopaedics and other specialties toward smaller-incision surgery. The purpose of this systematic review was to assess the effectiveness and safety of single mini-incision compared with standard-incision total hip replacement for treatment of arthritis of the hip.


We conducted an electronic literature search for relevant studies published in any language up to March 2010. Key conference proceedings and national orthopaedic registries were searched, professional organizations and implant manufacturers were approached, and reference lists from included studies were screened. We included randomized and quasi-randomized controlled trials assessing single mini-incision surgery, defined as an incision of ≤10 cm, compared with standard primary total hip replacement. Two reviewers independently assessed studies for inclusion and extracted data.


Fifteen randomized and five quasi-randomized controlled trials, involving 1857 participants, were eligible. Included trials were of mixed methodological quality, with the sample size ranging from twenty to 219. Mean follow-up periods were short, ranging from six weeks to three years. Compared with standard total hip replacement, mini-incision procedures may have small perioperative advantages in terms of less blood loss, shorter operative time, and shorter inpatient stay, but the differences were not clinically important. Few complications were reported, and the complication rate did not differ significantly between groups. There was insufficient evidence to suggest any major difference in the short-term revision rate, and confidence intervals for surrogate measures for long-term outcome were broad enough to include clinically important differences in favor of either approach.


Although there were marginal short-term advantages and disadvantages for each of the surgical techniques, there was no strong evidence either for or against mini-incision compared with standard-incision total hip replacement. Importantly, evidence on longer-term performance, especially the risk of revision arthroplasty, for mini-incision hip arthroplasty is very limited.

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    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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