0
Book Review   |    
BONE MORPHOGENETIC PROTEINS: BIOLOGY, BIOCHEMISTRY AND RECONSTRUCTIVE SURGERY. T. Sam Lindholm. Austin, Texas, R. G. Landes Company and Academic Press, 1996. $69.95, 311 pp.
Thomas A. Einhorn, M.D.
J Bone Joint Surg Am, 1997 Feb 01;79(2):318-318
5 Recommendations (Recommend) | 3 Comments | Saved by 3 Users Save Case

Extract

The concept that there is a substance in bone that can induce new-bone formation has been discussed for many years. However, the credit for the discovery of bone morphogenetic protein goes to Marshall R. Urist, who, in 1965, demonstrated the formation of bone by a process that he called autoinduction. With the subsequent identification of a family of molecules known as the bone morphogenetic proteins, clinicians and scientists from all fields of skeletal biology have gravitated to this area of investigation. The reason for this is obvious: if it is possible to develop a material that can be stored in an operating room and then implanted, injected, or otherwise introduced into a patient, the ability to enhance fracture-healing, skeletal reconstruction, and limb salvage after severe trauma could be revolutionized. Consequently, a book that effectively presents the results of thirty years of research on this topic, organizes them, and puts them in their proper perspective could be valuable. Dr. Lindholm has attempted to write such a book.
Figures in this Article

    First Page Preview

    View Large
    />
    First page PDF preview
    Sign In to Your Personal ProfileSign In To Access Full Content
    Not a Subscriber?
    Get online access for 30 days for $35
    New to JBJS?
    Sign up for a full subscription to both the print and online editions
    Register for a FREE limited account to get full access to all CME activities, to comment on public articles, or to sign up for alerts.
    Register for a FREE limited account to get full access to all CME activities
    Have a subscription to the print edition?
    Current subscribers to The Journal of Bone & Joint Surgery in either the print or quarterly DVD formats receive free online access to JBJS.org.
    Forgot your password?
    Enter your username and email address. We'll send you a reminder to the email address on record.

     
    Forgot your username or need assistance? Please contact customer service at subs@jbjs.org. If your access is provided
    by your institution, please contact you librarian or administrator for username and password information. Institutional
    administrators, to reset your institution's master username or password, please contact subs@jbjs.org

    References

    Accreditation Statement
    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
    CME Activities Associated with This Article
    Submit a Comment
    Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
    Comments are moderated and will appear on the site at the discretion of JBJS editorial staff.

    * = Required Field
    (if multiple authors, separate names by comma)
    Example: John Doe





    Related Content
    The Journal of Bone & Joint Surgery
    JBJS Case Connector
    Topic Collections
    Related Audio and Videos
    PubMed Articles
    Clinical Trials
    Readers of This Also Read...
    JBJS Jobs
    06/29/2012
    PA - Thomas Jefferson University
    04/02/2014
    IL - Hinsdale Orthopaedics
    03/26/2014
    MA - Boston University Orthopedic Surgical Associates