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Pathophysiology of Nerve Compression Syndromes: Response of Peripheral Nerves to Loading*
DAVID REMPEL, M.D., M.P.H.†, SAN FRANCISCO, CALIFORNIA; LARS DAHLIN, M.D., PH.D.‡; GÖRAN LUNDBORG, M.D., PH.D.‡, MALMÖ, SWEDEN
J Bone Joint Surg Am, 1999 Nov 01;81(11):1600-10
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Extract

Nerve compression syndromes involve peripheral-nerve dysfunction that is due to localized interference of microvascular function and structural changes in the nerve or adjacent tissues. Although a well known example is compression of the median nerve at the wrist (carpal tunnel syndrome), other nerves, such as the ulnar nerve at the wrist or the elbow and the spinal nerve roots at the vertebral foramen, are vulnerable. This paper focuses on studies in which the physiological, pathophysiological, biochemical, and histological effects of biomechanical loading on the peripheral nerves were evaluated in humans and animals.
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