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Current Concepts Review   |    
User's Guide to the Orthopaedic Literature: How to Use a Systematic Literature Review
Mohit Bhandari, MD, MSc; Gordon H. Guyatt, MD, MSc; Victor Montori, MD; P. J. Devereaux, MD; Marc F. Swiontkowski, MD
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Investigation performed at the Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Department of Medicine, Mayo Clinic, Rochester, Minnesota; and Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, Minnesota

Mohit Bhandari, MD, MSc
Gordon H. Guyatt, MD, MSc
P.J. Devereaux, MD
Department of Clinical Epidemiology and Biostatistics, McMaster University Health Sciences Center, Room 2C12, 1200 Main Street West, Hamilton, ON L8N 3Z5, Canada. E-mail address for: M. Bhandari: bhandari@sympatico.ca

Victor Montori, MD
Department of Medicine, Mayo Clinic, 200 First Street S.W., Rochester, MN 55905

Marc F. Swiontkowski, MD
Department of Orthopaedic Surgery, University of Minnesota, Box 492, Delaware Street N.E., Minneapolis, MN 55455

The authors did not receive grants or outside funding in support of their research or preparation of this manuscript. They did not receive payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the authors are affiliated or associated.

This article is the third in a series designed to help the orthopaedic surgeon use the published literature in practice. In the first article in the series, we presented guidelines for making a decision about therapy and focused on randomized controlled trials. In the second article, we focused on evaluating nonrandomized studies that present information about a patient's prognosis. In this article, we concentrate on systematic literature reviews.


J Bone Joint Surg Am, 2002 Sep 01;84(9):1672-1682
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• Investigators who perform a systematic review address a focused clinical question, conduct a thorough search of the literature, apply inclusion and exclusion criteria to each potentially eligible study, critically appraise the relevant studies, conduct sensitivity analyses, and synthesize the information to draw conclusions relevant to patient care or additional study.
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    Accreditation Statement
    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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