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Epinephrine-Induced Pulmonary Edema During Arthroscopic Knee Surgery A Case Report
Augustus D. Mazzocca, MD; R. Michael Meneghini, MD; Ramesh Chhablani, MD; Shyamala K. Badrinath, MD; Brian J. Cole, MDMBA; Charles A. Bush-Joseph, MD
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Investigation performed at Rush Medical College, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois

Augustus D. Mazzocca, MD
R. Michael Meneghini, MD
Ramesh Chhablani, MD
Shyamala K. Badrinath, MD
Brian J. Cole, MD, MBA
Charles A. Bush-Joseph, MD
Rush-Presbyterian-St. Luke's Medical Center, 1725 West Harrison Street, Chicago, IL 60612. E-mail address for C.A. Bush-Joseph: charles.bush-joseph@midwestortho.com

The authors did not receive grants or outside funding in support of their research or preparation of this manuscript. They did not receive payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the authors are affiliated or associated.

J Bone Joint Surg Am, 2003 May 01;85(5):913-915
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In recent reports, use of dilute epinephrine irrigation fluid has been recommended as a safe and effective way to improve visualization in arthroscopic knee and shoulder surgery 1,2 . We are not aware of any reports, in the orthopaedic literature, of adverse reactions to epinephrine utilized in this manner. The anesthesiology literature contains a single case report of nearly fatal ventricular tachycardia in a patient undergoing shoulder arthroscopy with use of dilute epinephrine irrigation fluid 3 . We present a case of nearly fatal cardiopulmonary collapse during arthroscopy of the knee in which dilute epinephrine irrigation fluid was utilized. The patient was informed that data concerning her case would be submitted for publication.
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    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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