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Case Reports   |    
Healing of a Chondral Fragment of the Knee in an Adolescent After Internal FixationA Case Report
Norimasa Nakamura, MD, PhD1; Shuji Horibe, MD, PhD2; Takehiko Iwahashi, MD2; Kiyoshi Kawano, MD2; Konsei Shino, MD, PhD1; Hideki Yoshikawa, MD, PhD1
1 Department of Orthopaedics, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan. E-mail address for N. Nakamura: n-nakamura@ort.med.osaka-u.ac.jp
2 Departments of Orthopaedic Sports Medicine (S.H. and T.I.) and Clinical Pathology (K.K.), Osaka Rosai Hospital, 1179-3 Nagasone-cho, Sakai, Osaka 591-8025, Japan
View Disclosures and Other Information
The authors did not receive grants or outside funding in support of their research or preparation of this manuscript. They did not receive payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the authors are affiliated or associated.
Investigation performed at Osaka Rosai Hospital, Osaka, Japan

The Journal of Bone and Joint Surgery, Incorporated
J Bone Joint Surg Am, 2004 Dec 01;86(12):2741-2746
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Extract

Articular cartilage lacks a blood supply and thus is regarded as having poor healing potential1-3. Specifically, it is widely accepted that a partial-thickness cartilage injury cannot heal spontaneously4-7. Therefore, a variety of approaches are under investigation to improve cartilage healing1-3. One of the options to facilitate healing is to recruit bone-marrow cells to the injured site by penetrating the subchondral bone; however, previous experimental and clinical studies have suggested that this approach typically leads to healing by the formation of fibrocartilage-like tissue over long periods of time1-3.
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    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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