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Rosai-Dorfman Disease of the Triquetrum Without LymphadenopathyA Case Report
Sir-Young Loh, MBBS(Singapore), FRCS(Edin), FRCS(Orth) (Edin)1; Kong-Bing Tan, MBBS(Singapore)2; Yue-Shuen Wong, MBBS(Singapore), FRCS(Edin), MSc, (Biomedical Eng)1; Yoke-Sun Lee, MBBS(Singapore), MRCP(UK), FRCPA, FAMS, MD2
1 Department of Orthopedic Surgery, Alexandra Hospital, 378 Alexandra Road, Singapore 159964. E-mail address for Dr. Wong: yueshuen@yahoo.com
2 Department of Pathology, National University of Singapore 5, Lower Kent Ridge Road, Singapore 119074
View Disclosures and Other Information
The authors did not receive grants or outside funding in support of their research or preparation of this work. They did not receive payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the authors are affiliated or associated.
Investigation performed at the Alexandra Hospital and National University Hospital, Singapore

The Journal of Bone and Joint Surgery, Incorporated
J Bone Joint Surg Am, 2004 Mar 01;86(3):595-598
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Extract

Sinus histiocytosis with massive lymphadenopathy, also known as Rosai-Dorfman disease, is a rare condition of marrow hemopoietic stem-cell origin. Most patients present with lymphatic involvement, whereas less than one-third of cases are extranodal presentations1. Extranodal cases present as space-occupying lesions, and it is necessary to exclude malignant tumor as a diagnosis. Only about 5% of the extranodal cases involve bone1, and these are often associated with extraosseous manifestations. Primary solitary osseous involvement is very uncommon. We report a case of Rosai-Dorfman disease with primary solitary involvement of the triquetrum without lymphadenopathy. This is an uncommon cause of an osseous lesion in the short bones of the hands and feet and, to our knowledge, it has not been described in the triquetrum previously.
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