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In Vivo Assessment of the Kinematics in Normal and Anterior Cruciate Ligament-Deficient Knees
Mohamed R. Mahfouz, PhD; Richard D. Komistek, PhD; Douglas A. Dennis, MD; William A. Hoff, PhD
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In support of their research or preparation of this manuscript, one or more of the authors received grants or outside funding from the National Science Foundation. None of the authors received payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the authors are affiliated or associated.

The Journal of Bone and Joint Surgery, Incorporated
J Bone Joint Surg Am, 2004 Dec 01;86(suppl 2):56-61
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Extract

The in vivo measurement of dynamic knee kinematics is important for understanding the effects of joint injuries and diseases and for evaluating the outcome of surgical procedures. Researchers have used in vitro approaches (involving cadavers), noninvasive approaches (involving studies done at gait laboratories), and in vivo approaches (involving roentgen stereophotogrammetry and fluoroscopy) to assess human knee motion. To ensure that the loads that are encountered during typical movements are accurately incorporated, treatments that are aimed at improving knee function should be evaluated with use of data that are obtained with dynamic measurement methods. This requires that the six-degrees-of-freedom pose (position and orientation) of objects be measured during dynamic activities. The purpose of the current study was to accurately determine the three-dimensional kinematic patterns of normal and anterior cruciate ligament-deficient knees during in vivo weight-bearing activities with use of a novel intensity-based two-dimensional to three-dimensional image registration method, similar to that previously utilized to analyze the kinematics of total knee arthroplasty1.
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    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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