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Pleomorphic Malignant Fibrous Histiocytoma at the Site of an Arthroscopic Reconstruction of the Anterior Cruciate LigamentA Case Report
François Sirveaux, MD, PhD1; Nicolas Hummer, MD1; Olivier Roche, MD1; Maria Rios, MD2; Jean-Michel Vignaud, MD2; Daniel Molé, MD1
1 Clinique de Traumatologie et d'Orthopédie, 49 rue Hermite, 54000 Nancy, France. E-mail address for F. Sirveaux: francois.sirveaux@wanadoo.fr
2 Centre Alexis Vautrin, 6 avenue de Bourgogne, 54500 Vandoeuvre les Nancy, France
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The authors did not receive grants or outside funding in support of their research or preparation of this manuscript. They did not receive payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the authors are affiliated or associated.
Investigation performed at the Clinique de Traumatologie et d'Orthopédie, Nancy, France

The Journal of Bone and Joint Surgery, Incorporated
J Bone Joint Surg Am, 2005 Feb 01;87(2):404-409. doi: 10.2106/JBJS.C.01207
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Previously regarded as a distinct tumor type representing the most common adult soft-tissue sarcoma1,2, the term malignant fibrous histiocytoma is now reserved for a small group of undifferentiated pleomorphic sarcomas3. The tumor is most often primary, but rare cases of secondary malignant fibrous histiocytoma in burn scars4-8 or infected or noninfected surgical scars9-12 have been reported (see Appendix). Secondary malignant fibrous histiocytoma has been described in contact with prostheses13-28, osteosynthesis material29-35, or implanted Dacron grafts36. Malignant degeneration of benign tumors35, Paget disease37, osseous infarcts38, or fibrous dysplasia39 also has been reported (see Appendix). We report a unique case of a patient with soft-tissue malignant fibrous histiocytoma that developed on the medial side of the knee six years after arthroscopic reconstruction of the anterior cruciate ligament with use of the patellar tendon.
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