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Knee Pain and Swelling Due to Crohn DiseaseA Case Report
Lieutenant Mariusz A. Olszewski, MD1; Commander Richard E. Manos, MD2; Commander Peter J. Weis, MD3; Lieutenant Commander Matthew T. Provencher, MD4
1 Medical Corps, United States Naval Reserve
2 Medical Corps, United States Naval Reserve
3 Medical Corps, United States Naval Reserve
4 Medical Corps, United States Naval Reserve Departments of Orthopaedic Surgery (M.A.O., R.E.M., and M.T.P.) and Rheumatology (P.J.W.), Naval Medical Center San Diego, 34800 Bob Wilson Drive, Suite 112, San Diego, CA 92134-1112
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The authors did not receive grants or outside funding in support of their research or preparation of this manuscript. They did not receive payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the authors are affiliated or associated.
The views expressed in this article are those of the authors and do not reflect the official policy or position of the Department of the Navy, the Department of Defense, or the United States government.
Investigation performed at the Departments of Orthopaedic Surgery and Rheumatology, Naval Medical Center San Diego, San Diego, California

The Journal of Bone and Joint Surgery, Incorporated
J Bone Joint Surg Am, 2005 Aug 01;87(8):1844-1847. doi: 10.2106/JBJS.D.01822
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Although peripheral arthritis is the most common extra-intestinal manifestation of inflammatory bowel disease, it is very rarely addressed in the orthopaedic literature. The overwhelming majority of patients with inflammatory bowel disease present with gastrointestinal symptoms and do not have any joint involvement until much later. We present the case of a patient who had joint pain and swelling but lacked any sign of gastrointestinal involvement. After five months of work-up, the patient was diagnosed with Crohn disease and the joint symptoms improved with appropriate medical treatment. We believe that inflammatory bowel disease should be considered in the differential diagnosis of joint pain and swelling. Our patient was informed that data concerning the case would be submitted for publication.
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