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Biomechanical and Clinical Evaluations of a Porous Tantalum Implant for the Treatment of Early-Stage Osteonecrosis
A.K. Tsao, MD; J.R. Roberson, MD; M.J. Christie, MD; D.D. Dore, MD; D.A. Heck, MD; D.D. Robertson, MD, PHD; R.A. Poggie, PHD
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In support of their research or preparation of this manuscript, one or more of the authors received grants or outside funding from Implex Corporation and Zimmer. In addition, one or more of the authors received payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity (Implex Corporation and Zimmer). Also, a commercial entity (Implex Corporation and Zimmer) paid or directed, or agreed to pay or direct, benefits to research fund, foundation, educational institution, or other charitable or nonprofit organization with which the authors are affiliated or associated.

The Journal of Bone and Joint Surgery, Incorporated
J Bone Joint Surg Am, 2005 Dec 01;87(suppl 2):22-27. doi: 10.2106/JBJS.E.00490
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Osteonecrosis of the femoral head is a debilitating disease, caused by disruption of the blood supply to the femoral head, that typically affects the younger population1,2. Etiologies include alcoholism, use of steroidal drugs, trauma, blood disorders, radiation therapy, and dysbaria1-3. In the United States, it is estimated that 10,000 to 30,000 cases occur annually and that 5% to 12% of total hip arthroplasties are performed to treat the disease2. Surgical intervention is likely to be more effective when performed in the early stages of osteonecrosis, prior to collapse of the femoral head and subchondral plate. In these early stages, the pathological process is usually confined to a wedge-shaped area of necrosis in the superior weight-bearing portion of the femoral head. As the disease progresses, this area is subject to collapse and the occurrence of a fracture at the junction of living and dead bone.
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