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Letters to the Editor   |    
Comparison of Soap and Antibiotic Solutions for Irrigation of Lower-Limb Open Fracture Wounds
Manoj Todkar, MRCS, MS(Orth), DNB1
1 Department of OrthopaedicsFlat 27, Peterson Hall, 25 RoseangleDundee DD1 4LSScotland, United Kingdom mtodkar@hotmail.com
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The author did not receive grants or outside funding in support of his research for or preparation of this manuscript. He did not receive payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the author is affiliated or associated.

The Journal of Bone and Joint Surgery, Incorporated
J Bone Joint Surg Am, 2006 Feb 01;88(2):452-452
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Extract

To The Editor:I read the article entitled "Comparison of Soap and Antibiotic Solutions for Irrigation of Lower-Limb Open Fracture Wounds. A Prospective, Randomized Study" (2005;87: 1415-22), by Anglen, with great interest. The topic is of interest to all orthopaedic surgeons who deal with open fractures in their practice.We have used a number of different solutions, including saline solution, soap, antibiotic, chlorhexidine, Betadine, and hydrogen peroxide. The most important factor, in my view, is the use of copious pulse lavage, which mechanically removes the debris and bacteria from an open wound. It has been suggested that at least a few liters of saline solution (rather than hydrogen peroxide) should be used for irrigation because in some open wounds, debris is driven deep into tissues with the foaming action of hydrogen peroxide.
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