Scientific Articles   |    
Lack of Seasonal Variation in Idiopathic Talipes Equinovarus
Randall T. Loder, MD1; David M. Drvaric, MD2; Brian Carney, MD3; Zachary Hamby, MD4; Simon Barker, MD5; David Chesney, MD6; Nicola Maffulli, MD7
1 James Whitcomb Riley Hospital for Children, Room 4250, 702 Barnhill Drive, Indianapolis, IN 46202. E-mail address: rloder@iupui.edu
2 Shriners Hospital for Children, 516 Carew Street, Springfield, MA 01104
3 Dartmouth-Hitchcock Medical Center, Pediatric Orthopaedics, One Medical Center Drive, Lebanon, NH 03756
4 Atlanta Medical Center, 303 Parkway Drive, NE, Box 423, Atlanta, GA 30312
5 University of Aberdeen Medical School, Aberdeen AB25 2ZD, Scotland
6 Department of Trauma and Orthopaedic Surgery, Freeman Hospital, Freeman Road, High Heaton, Newcastle upon Tyne, NE7 7DN, England
7 Keele University School of Medicine, Thornburrow Drive, Hartshill, Stoke on Trent, Staffordshire, ST4 6QG, England
View Disclosures and Other Information
In support of their research for or preparation of this manuscript, one or more of the authors received grants or outside funding from the Garceau Professorship Endowment, the Rapp Pediatric Orthopaedic Research Endowment, SPARKS (Sport Aiding Medical Research for Kids), and Grampian Health Authority Research Endowment Fund. None of the authors received payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the authors are affiliated or associated.
Investigation performed at James Whitcomb Riley Hospital for Children, Indianapolis, Indiana

The Journal of Bone and Joint Surgery, Incorporated
J Bone Joint Surg Am, 2006 Mar 01;88(3):496-502. doi: 10.2106/JBJS.E.00093
5 Recommendations (Recommend) | 3 Comments | Saved by 3 Users Save Case


Background: One proposed etiology of idiopathic talipes equinovarus is an in utero enterovirus infection. Enterovirus infections demonstrate seasonal variation in temperate climates.

Methods: We collected data on 1202 children with idiopathic talipes equinovarus born in the Northeastern United States, Midwestern United States, and the United Kingdom to investigate a seasonal variation in this congenital deformity. Birth date, gestational age at the time of delivery, gender, race, and laterality were tabulated and subjected to univariate and bivariate analyses.

Results: There were 774 boys and 428 girls with idiopathic talipes equinovarus. The birth location was the United Kingdom (458 children), the Midwestern United States (426 children), and the Northeastern United States (318 children). No significant differences were detected among the geographic groups with respect to gender, race, or laterality, and no variation in month of birth or month of conception was noted.

Conclusions: This study does not support an in utero enterovirus infection as an etiology of idiopathic talipes equinovarus in industrialized populations.

Figures in this Article
    Sign In to Your Personal ProfileSign In To Access Full Content
    Not a Subscriber?
    Get online access for 30 days for $35
    New to JBJS?
    Sign up for a full subscription to both the print and online editions
    Register for a FREE limited account to get full access to all CME activities, to comment on public articles, or to sign up for alerts.
    Register for a FREE limited account to get full access to all CME activities
    Have a subscription to the print edition?
    Current subscribers to The Journal of Bone & Joint Surgery in either the print or quarterly DVD formats receive free online access to JBJS.org.
    Forgot your password?
    Enter your username and email address. We'll send you a reminder to the email address on record.

    Forgot your username or need assistance? Please contact customer service at subs@jbjs.org. If your access is provided
    by your institution, please contact you librarian or administrator for username and password information. Institutional
    administrators, to reset your institution's master username or password, please contact subs@jbjs.org


    Accreditation Statement
    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
    CME Activities Associated with This Article
    Submit a Comment
    Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
    Comments are moderated and will appear on the site at the discretion of JBJS editorial staff.

    * = Required Field
    (if multiple authors, separate names by comma)
    Example: John Doe

    Related Content
    The Journal of Bone & Joint Surgery
    JBJS Case Connector
    Topic Collections
    Related Audio and Videos
    PubMed Articles
    Clinical Trials
    Readers of This Also Read...
    JBJS Jobs
    S. Carolina - Department of Orthopaedic Surgery Medical Univerity of South Carlonina
    New York - Icahn School of Medicine at Mount Sinai
    W. Virginia - Charleston Area Medical Center
    District of Columbia (DC) - Children's National Medical Center