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Necrotizing Fasciitis Caused by Methicillin-Resistant Staphylococcus aureus Resulting in DeathA Report of Three Cases
Nai-Chen Cheng, MD1; Shan-Chwen Chang, MD, PhD1; Yuan-Sung Kuo, MD1; Jiun-Ling Wang, MD1; Yueh-Bih Tang, MD, PhD1
1 Departments of Surgery (N.-C.C., Y.-S.K., and Y.-B.T.) and Internal Medicine (S.-C.C. and J.-L.W.), National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei 100, Taiwan. E-mail address for Y.-B. Tang: phoebe@ha.mc.ntu.edu.tw
View Disclosures and Other Information
The authors did not receive grants or outside funding in support of their research for or preparation of this manuscript. They did not receive payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the authors are affiliated or associated.
Investigation performed at the Departments of Surgery and Internal Medicine, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan

The Journal of Bone and Joint Surgery, Incorporated
J Bone Joint Surg Am, 2006 May 01;88(5):1107-1110. doi: 10.2106/JBJS.E.01048
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Extract

Necrotizing fasciitis is a life-threatening infection of the superficial muscle fascia and adjacent subcutaneous tissue. These infections are typically caused by group-A Streptococcus, a mixture of aerobic and anaerobic organisms, or organisms of the Clostridia species1. Staphylococcus aureus has been occasionally reported as a monomicrobial causative agent of necrotizing fasciitis, and methicillin-resistant Staphylococcus aureus was described as the cause of two cases of hospital-associated necrotizing fasciitis2,3. Nevertheless, over the past few years, the incidence of community-acquired methicillin-resistant Staphylococcus aureus infection has substantially increased4,5. The majority of these infections are of the skin and soft tissues5,6.
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