R.J.K. Khan, M. Parker, D. Fick, and A. Keogh reply:We thank Mr. Dobson and Mr. Nguyen for their letter. The issue that they
raise is one of semantics. Randomized trials may be blinded (e.g., with use of
random numbers or sealed identical envelopes) or quasi-randomized (e.g., with
use of alternation or odd/even numbers). Therefore, we believe that our title
is not misleading. Moreover, the inclusion of such studies is accepted
protocol for other evidence-based organizations such as Cochrane.