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Detection of Posttraumatic Cartilage Injury Using Quantitative T1rho Magnetic Resonance ImagingA Report of Two Cases with Arthroscopic Findings
Jesus Lozano, BS1; Xiaojuan Li, PhD1; Thomas M. Link, MD1; Marc Safran, MD2; Sharmila Majumdar, PhD1; C. Benjamin Ma, MD2
1 Musculoskeletal and Quantitative Imaging Research Group (MQIR), Department of Radiology, University of California at San Francisco, 185 Berry Street, Suite 350, San Francisco, CA 94107
2 Department of Orthopaedic Surgery, University of California at San Francisco, 500 Parnassus Avenue, MU 320W, San Francisco, CA 94143. E-mail address for C.B. Ma: maben@orthosurg.ucsf.edu
View Disclosures and Other Information
The authors did not receive grants or outside funding in support of their research for or preparation of this manuscript. They did not receive payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the authors are affiliated or associated.
Investigation performed at the Department of Orthopaedic Surgery, University of California at San Francisco, San Francisco, California

The Journal of Bone and Joint Surgery, Incorporated
J Bone Joint Surg Am, 2006 Jun 01;88(6):1349-1352. doi: 10.2106/JBJS.E.01051
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Extract

Cartilage injuries following trauma are a common problem and can lead to premature, secondary osteoarthritis. Standard magnetic resonance imaging techniques can detect cartilage breakdown associated with morphological changes, such as decreases in cartilage thickness and volume, but it cannot detect early changes of the cartilage matrix. There is a need for a noninvasive method with which to diagnose articular cartilage abnormalities at early stages in order to initiate early treatment prior to the macroadaptive changes seen on radiographs.
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    Accreditation Statement
    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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