Question: In patients having total hip replacement (THR) or total
knee replacement (TKR), is wound closure with 2-octylcyanoacrylate (OCA)
superior to skin staples or subcuticular sutures?Design: Randomized (unclear allocation concealment), blinded
(patients and outcome assessors), controlled trial with 8 to 12-week
follow-up.Setting: An orthopaedic institute and hospital in Perth, Western
Australia, Australia.Patients: 102 patients having THR (median age range, 69 to 71 y; 51%
women) and 85 patients having TKR (median age range, 66 to 73 y; 56% women).
Exclusion criteria were planned revision, previous incision in the operative
area, history of keloid formation, allergy to superglue (SuperGlue, Rancho
Cucamonga, California), regular anticoagulation therapy, or underlying
malignancy. Follow-up was 100%.