Evidence-Based Orthopaedics   |    
Varus Alignment Was Associated with an Increased Risk of Osteoarthritis of the Knee

View Disclosures and Other Information
Sources of funding: Not stated.
For correspondence: Dr. S.M.A. Bierma-Zeinstra, Department of General Practice, Erasmus Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands. E-mail address: s.bierma-zeinstra@erasmusmc.nl.
Brouwer GM, van Tol AW, Bergink AP, Belo JN, Bernsen RMD, Reijman M, Pols HAP, Bierma-Zeinstra SMA. Association Between Valgus and Varus Alignment and the Development and Progression of Radiographic Osteoarthritis of the Knee.
Arthritis Rheum
. 2007Apr;56: 1204-11.

The Journal of Bone and Joint Surgery, Incorporated
J Bone Joint Surg Am, 2007 Nov 01;89(11):2557-2557. doi: 10.2106/JBJS.8911.ebo2
5 Recommendations (Recommend) | 3 Comments | Saved by 3 Users Save Case


Question: Is malalignment associated with the development of osteoarthritis of the knee?Design: Cohort population-based study.Setting: Rotterdam, The Netherlands.Patients: 1501 participants (3002 knees) =55 years of age (mean age, 66 y; 60% women) were randomly selected from 3585 participants who completed 6.6 years of follow-up. Of the 3002 knees, 2664 had legible radiographs.Assessment of risk factors: Knees were categorized as having normal alignment (medial angle formed by the femur and tibia [FT angle] = 182° to 184°), varus alignment (FT angle <182°), or valgus alignment (FT angle >184°).
Figures in this Article

    First Page Preview

    View Large
    First page PDF preview
    Sign In to Your Personal ProfileSign In To Access Full Content
    Not a Subscriber?
    Get online access for 30 days for $35
    New to JBJS?
    Sign up for a full subscription to both the print and online editions
    Register for a FREE limited account to get full access to all CME activities, to comment on public articles, or to sign up for alerts.
    Register for a FREE limited account to get full access to all CME activities
    Have a subscription to the print edition?
    Current subscribers to The Journal of Bone & Joint Surgery in either the print or quarterly DVD formats receive free online access to JBJS.org.
    Forgot your password?
    Enter your username and email address. We'll send you a reminder to the email address on record.

    Forgot your username or need assistance? Please contact customer service at subs@jbjs.org. If your access is provided
    by your institution, please contact you librarian or administrator for username and password information. Institutional
    administrators, to reset your institution's master username or password, please contact subs@jbjs.org


    Accreditation Statement
    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
    CME Activities Associated with This Article
    Submit a Comment
    Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
    Comments are moderated and will appear on the site at the discretion of JBJS editorial staff.

    * = Required Field
    (if multiple authors, separate names by comma)
    Example: John Doe

    Related Content
    The Journal of Bone & Joint Surgery
    JBJS Case Connector
    Topic Collections
    Related Audio and Videos
    PubMed Articles
    Clinical Trials
    Readers of This Also Read...
    JBJS Jobs
    Ohio - OhioHealth Research and Innovation Institute (OHRI)
    Pennsylvania - Penn State Milton S. Hershey Medical Center
    Oregon - The Center - Orthopedic and Neurosurgical Care and Research