Evidence-Based Orthopaedics   |    
Arthroscopic Lavage Plus Corticosteroids Was More Effective Than Arthroscopic Lavage Plus Placebo or Joint Aspiration Plus Corticosteroids for Arthritis of the Knee

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Source of funding: No external funding.
For correspondence: Dr. J.M. van Laar, Leiden University Medical Center, Department of Rheumatology, Leiden, The Netherlands. E-mail address: j.m.van_laar@lumc.nl
van Oosterhout M, Sont JK, Bajema IM, Breedveld FC, van Laar JM. Comparison of Efficacy of Arthroscopic Lavage Plus Administration of Corticosteroids, Arthroscopic Lavage Plus Administration of Placebo, and Joint Aspiration Plus Administration of Corticosteroids in Arthritis of the Knee: A Randomized Controlled Trial.
Arthritis Rheum.
2006Dec15;55: 964-70.

The Journal of Bone and Joint Surgery, Incorporated
J Bone Joint Surg Am, 2007 May 01;89(5):1137-1137. doi: 10.2106/JBJS.8905.ebo1
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Question: In patients with inflammatory arthritis, what is the relative effectiveness of arthroscopic lavage plus corticosteroids, arthroscopic lavage alone, and joint aspiration plus corticosteroids?Design: Randomized (allocation concealed), partially blinded (outcome assessors), placebo-controlled trial with 9-month follow-up.Setting: A university medical center in The Netherlands.Patients: 78 patients who were =18 years of age (mean age 54 y, 55% women) and had arthritis of the knee not due to gout, osteoarthritis, or infection. Exclusion criteria were hemorrhagic disease, oral prednisone >10 mg/day, recent (<6 weeks) change of disease-modifying antirheumatic drugs, recent joint infection, or hypersensitivity to methylprednisolone or local anesthetics. Follow-up was 96%.
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