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Isolated Left-Sided Metastatic Sarcoma of the Heart with Limb IschemiaA Case Report
Aditya V. Maheshwari, MD1; Carlos A. Muro-Cacho, MD1; Jonathan J. Cohen, MD1; Martin Keisch, MD1; Roman B. Klos, MD2; H. Thomas Temple, MD1
1 Division of Musculoskeletal Oncology, Departments of Orthopedics (A.V.M. and H.T.T.), Pathology (C.A.M.-C.), Hematology/Oncology (J.J.C.), and Radiation Oncology (M.K.), University of Miami Miller School of Medicine, Cedars Medical Center, Suite 4036 East, 1400 N.W. 12th Avenue, Miami, FL 33136. E-mail address for A.V. Maheshwari: adi_maheshwari@rediffmail.com
2 Department of Cardiothoracic Surgery, Broward General Medical Center, 1600 South Andrews Avenue, Fort Lauderdale, FL 33316
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Disclosure: The authors did not receive any outside funding or grants in support of their research for or preparation of this work. Neither they nor a member of their immediate families received payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, division, center, clinical practice, or other charitable or nonprofit organization with which the authors, or a member of their immediate families, are affiliated or associated.
Investigation performed at University of Miami Miller School of Medicine, Miami, Florida

The Journal of Bone and Joint Surgery, Inc.
J Bone Joint Surg Am, 2008 May 01;90(5):1112-1116. doi: 10.2106/JBJS.G.00788
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Soft-tissue sarcomas are rare causes of metastatic tumors of the heart1,2, which often involve the right side of the heart and rarely present as intracavitary lesions1,2. Despite their frequency of occurrence, metastatic cardiac tumors often remain subclinical since symptoms of disseminated disease prevail. An isolated metastatic heart tumor is rare and may present with a spectrum of clinical signs and symptoms1,3-5. We present the case of a patient who had an isolated left-sided metastatic heart tumor along with a coexisting atrial septal defect. The tumor presented as acute thromboembolic limb ischemia three months after neoadjuvant chemotherapy, wide local resection, and brachytherapy for a high-grade undifferentiated pleomorphic sarcoma of the contralateral calf. The husband of our patient was informed that data concerning the case would be submitted for publication, and he consented.
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