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Autologous Chondrocyte Implantation in the Knee Joint: Open Compared with Arthroscopic TechniqueComparison at a Minimum Follow-up of Five Years
Alberto Ferruzzi, MD1; Roberto Buda, MD1; Cesare Faldini, MD1; Francesca Vannini, MD1; Francesco Di Caprio, MD1; Deianira Luciani, MD1; Sandro Giannini, MD1
1 Department of Orthopaedic Surgery, University of Bologna, Istituto Ortopedico Rizzoli, Via G.C. Pupilli 1, Bologna 40136, Italy
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Disclosure: The authors did not receive any outside funding or grants in support of their research for or preparation of this work. Neither they nor a member of their immediate families received payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, division, center, clinical practice, or other charitable or nonprofit organization with which the authors, or a member of their immediate families, are affiliated or associated.

The Journal of Bone and Joint Surgery, Incorporated
J Bone Joint Surg Am, 2008 Nov 01;90(Supplement 4):90-101. doi: 10.2106/JBJS.H.00633
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Autologous chondrocyte implantation is a widely used technique for treating cartilage lesions1-10. The technique, first introduced and described by Brittberg et al. in 199411, required an arthrotomy of the joint, débridement of the lesions, and the suturing of a periosteal flap to create a pocket to host the chondrocytes. Autologous chondrocyte implantation in the knee joint has provided hyaline-like repair tissue11-16, with satisfactory clinical results in 80% to 90% of patients1,7,17. Moreover, autologous chondrocyte implantation has been shown to be a valid alternative to the mosaicplasty and microfracture repair techniques used in the treatment of osteochondral lesions of the knee1,6,13,17-20.
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