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Tuberculous Arthritis of the Knee Treated with Two-Stage Total Knee ArthroplastyA Case Report
Lance E. Leclere, MD1; V. Franklin SechriestII, MD1; Keith G. Holley, MD1; Dean T. Tsukayama, MD2
1 Department of Orthopaedic Surgery, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA 92134. E-mail address for V.F. Sechriest II: vernon.sechriest@med.navy.mil
2 Division of Infectious Diseases, Department of Medicine, Hennepin County Medical Center, 701 Park Avenue South, Minneapolis, MN 55415
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Disclosure: The authors did not receive any outside funding or grants in support of their research for or preparation of this work. Neither they nor a member of their immediate families received payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, division, center, clinical practice, or other charitable or nonprofit organization with which the authors, or a member of their immediate families, are affiliated or associated.
Disclaimer: The views expressed in this article are those of the authors and do not reflect the official policy or position of the Department of the Navy, the Department of Defense, or the United States Government.
Investigation performed at Naval Medical Center, San Diego, California

The Journal of Bone and Joint Surgery, Inc.
J Bone Joint Surg Am, 2009 Jan 01;91(1):186-191. doi: 10.2106/JBJS.G.01421
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Extract

It has been estimated that 2 billion people worldwide currently have tuberculosis in its latent form and that the active form of the disease will develop in 8 million people annually1. Tuberculous arthritis of the knee is one of the most common musculoskeletal manifestations2-6. While chemotherapy remains the cornerstone of treatment7, surgery of the knee may also be indicated and has been reported to include débridement and synovectomy8-10, arthrodesis11-14, amputation15-18, resection arthroplasty19-23, and prosthetic joint replacement24. Recently, there have been several reports of successful management of tuberculous arthritis of the knee with primary total knee arthroplasty25-31.
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    Accreditation Statement
    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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