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Case Reports   |    
Bilateral Metal-on-Metal Hybrid Hip Resurfacing in a Patient with OsteopetrosisA Case Report
Chen-Ti Wang, MD, PhD1; Harlan C. Amstutz, MD2
1 Department of Orthopedics, National Taiwan University Hospital and National Taiwan University College of Medicine, Number 7, Chung-Shan South Road, Taipei, Taiwan
2 Joint Replacement Institute, The S. Mark Taper Building, 2200 West Third Street, Suite 400, Los Angeles, CA 90057. E-mail address: harlanamstutz@dochs.org
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Disclosure: In support of their research for or preparation of this work, one or more of the authors received, in any one year, outside funding or grants in excess of $10,000 from Wright Medical Technology. In addition, one or more of the authors or a member of his or her immediate family received, in any one year, payments or other benefits in excess of $10,000 or a commitment or agreement to provide such benefits from a commercial entity (Wright Medical Technology). Also, a commercial entity (Wright Medical Technology) paid or directed in any one year, or agreed to pay or direct, benefits in excess of $10,000 to a research fund, foundation, division, center, clinical practice, or other charitable or nonprofit organization with which one or more of the authors, or a member of his or her immediate family, is affiliated or associated.
Investigation performed at the Joint Replacement Institute at Saint Vincent Medical Center, Los Angeles, California

The Journal of Bone and Joint Surgery, Inc.
J Bone Joint Surg Am, 2009 Dec 01;91(12):2941-2944. doi: 10.2106/JBJS.H.01430
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Extract

Osteopetrosis, also known as marble bone disease1, is a rare inherited skeletal condition characterized by failure of osteoclast-mediated bone resorption. Orthopaedic surgeons most commonly encounter patients with the benign autosomal-dominant type of adult-onset osteopetrosis, who often first learn of their diagnosis after sustaining a fracture. The lifelong prevalence of fractures in this patient group ranges from 40% to 66.6%2-5. Other clinical manifestations include coxa vara (caused by stress-induced microfractures in the femoral neck), spine problems (scoliosis, spondylolysis, cervical spine fractures, and idiopathic low back pain), osteomyelitis, and cranial nerve compression syndromes.
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    Accreditation Statement
    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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