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Selected Instructional Course Lecture   |    
Surgical Management of Articular Cartilage Defects in the Knee
Brian J. Cole, MD, MBA1; Cecilia Pascual-Garrido, MD1; Robert C. Grumet, MD1
1 Departments of Orthopedic Surgery (B.J.C., C.P.-G., and R.C.G.) and Anatomy and Cell Biology (B.J.C.), Rush University Medical Center, 1725 West Harrison Street, Suite 1063, Chicago, IL 60612. E-mail address for B.J. Cole: bcole@rushortho.com. E-mail address for C. Pascual-Garrido: cecilia.pascualgarrido@gmail.com. E-mail address for R.C. Grumet: rgrumet@gmail.com
View Disclosures and Other Information
Disclosure: The authors did not receive any outside funding or grants in support of their research for or preparation of this work. Neither they nor a member of their immediate families received payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity.
Printed with permission of the American Academy of Orthopaedic Surgeons. This article, as well as other lectures presented at the Academy's Annual Meeting, will be available in March 2010 in Instructional Course Lectures, Volume 59. The complete volume can be ordered online at www.aaos.org, or by calling 800-626-6726 (8 a.m.-5 p.m., Central time).
An Instructional Course Lecture, American Academy of Orthopaedic Surgeons

The Journal of Bone and Joint Surgery, Inc.
J Bone Joint Surg Am, 2009 Jul 01;91(7):1778-1790
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Extract

Articular cartilage is vulnerable to traumatic injury and subsequent degeneration. These changes are likely related to the limited capacity for cartilage repair, poor vascular supply, and deficiency in terms of the ability of an undifferentiated cell population to respond to the insult. While the natural history of isolated chondral and osteochondral defects is not predictable, clinical experience suggests that, when left untreated, these lesions do not heal and may progress to symptomatic degeneration of the joint1. Therefore, early surgical intervention for symptomatic lesions is often suggested in an effort to restore normal joint congruity and pressure distribution and prevent further injury. Treatment recommendations are made after an evaluation of symptomatic lesions and should be tailored to the specifics of each case.
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    Accreditation Statement
    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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