0
Instructional Course Lecture   |    
Malignant Bone Tumors
C. Parker GibbsJr., MD; Kristy Weber, MD; Mark T. Scarborough, MD
J Bone Joint Surg Am, 2001 Nov 01;83(11):1728-1745
5 Recommendations (Recommend) | 3 Comments | Saved by 3 Users Save Case

Extract

Classic high-grade osteosarcoma is a highly malignant spindle-cell sarcoma of bone in which the malignant cells produce osteoid1. It is the most common primary malignant tumor of bone, excluding myeloma, and is the third most common malignant disease in adolescence after leukemia and lymphoma. However, it is still a rare tumor with only 1000 new cases per year in the United States. There appears to be no racial or ethnic influence associated with its incidence2. However, an increased prevalence has been noted in families affected with the Li-Fraumeni syndrome3 and in patients who have had retinoblastoma4 (a 40% prevalence in those with bilateral disease), have undergone radiation therapy5, or have Paget disease6.
Figures in this Article

    First Page Preview

    View Large
    />
    First page PDF preview
    Sign In to Your Personal ProfileSign In To Access Full Content
    Not a Subscriber?
    Get online access for 30 days for $35
    New to JBJS?
    Sign up for a full subscription to both the print and online editions
    Register for a FREE limited account to get full access to all CME activities, to comment on public articles, or to sign up for alerts.
    Register for a FREE limited account to get full access to all CME activities
    Have a subscription to the print edition?
    Current subscribers to The Journal of Bone & Joint Surgery in either the print or quarterly DVD formats receive free online access to JBJS.org.
    Forgot your password?
    Enter your username and email address. We'll send you a reminder to the email address on record.

     
    Forgot your username or need assistance? Please contact customer service at subs@jbjs.org. If your access is provided
    by your institution, please contact you librarian or administrator for username and password information. Institutional
    administrators, to reset your institution's master username or password, please contact subs@jbjs.org

    References

    Accreditation Statement
    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
    CME Activities Associated with This Article
    Submit a Comment
    Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
    Comments are moderated and will appear on the site at the discretion of JBJS editorial staff.

    * = Required Field
    (if multiple authors, separate names by comma)
    Example: John Doe





    Related Content
    The Journal of Bone & Joint Surgery
    JBJS Case Connector
    Topic Collections
    Related Audio and Videos
    PubMed Articles
    Clinical Trials
    Readers of This Also Read...
    JBJS Jobs
    04/16/2014
    OH - OhioHealth Research and Innovation Institute (OHRI)
    02/28/2014
    DC - Children's National Medical Center
    03/05/2014
    OK - The University of Oklahoma
    12/04/2013
    NY - Icahn School of Medicine at Mount Sinai