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Scientific Articles   |    
Failure Patterns After Linked Semiconstrained Total Elbow Arthroplasty for Posttraumatic Arthritis
Thomas Throckmorton, MD1; Peter Zarkadas, MD1; Joaquin Sanchez-Sotelo, MD, PhD1; Bernard Morrey, MD1
1 Department of Orthopedics, Mayo Clinic, 200 First Avenue S.W., Rochester, MN 55906. E-mail address for J. Sanchez-Sotelo: sanchezsotelo.joaquin@mayo.edu
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Disclosure: The authors did not receive any outside funding or grants in support of their research for or preparation of this work. One or more of the authors, or a member of his or her immediate family, received, in any one year, payments or other benefits in excess of $10,000 or a commitment or agreement to provide such benefits from a commercial entity (Zimmer, Stryker, DePuy).

Investigation performed at the Department of Orthopedics, Mayo Clinic, Rochester, Minnesota

Copyright ©2010 American Society for Journal of Bone and Joint Surgery, Inc.
J Bone Joint Surg Am, 2010 Jun 01;92(6):1432-1441. doi: 10.2106/JBJS.I.00145
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Abstract

Background: 

Total elbow arthroplasty for the treatment of posttraumatic arthritis is associated with a relatively high failure rate. An understanding of these failures can lead to improved implant design and surgical technique.

Methods: 

Eighty-four consecutive patients underwent eighty-five semiconstrained total elbow arthroplasties for the treatment of posttraumatic arthritis. Sixty-nine elbows with a retained primary prosthesis were followed for an average of nine years. Clinical results were graded with use of the Mayo Elbow Performance Score. Radiographs were assessed for mechanical failure, and all complications were recorded.

Results: 

Sixteen primary arthroplasties (19%) failed. Causes of failure included isolated bushing wear (seven), infection (four), component fracture (three), and component loosening (two). The most common cause of early failure (failure after less than five years) was infection, whereas intermediate-term failure (failure after five to ten years) typically was due to bushing wear. Late failure (failure after more than ten years) was uncommon and involved component loosening or fracture. Seventy-five percent of the failures were in patients who were less than sixty years old at the time of surgery (p = 0.03). Progressive radiolucent lines were noted around four implants, three of which had clinically important loosening. Total elbow arthroplasty was associated with significant improvements in terms of pain, motion, and the Mayo Elbow Performance Scores (p = 0.002). Sixty-eight percent of the patients achieved a good or excellent clinical result, and 74% were subjectively satisfied. Kaplan-Meier analysis demonstrated a fifteen-year survival rate of 70% with revision or resection for any reason as the end point.

Conclusions: 

Semiconstrained total elbow arthroplasty in patients with posttraumatic arthritis places high demands on the implant and is associated with a relatively high failure rate. Seventy-five percent of failures occur in patients less than sixty years of age, and infection continues to represent a frequent mode of early failure. Bushing wear and component loosening or fracture are seen more commonly in the intermediate and late term, whereas aseptic loosening remains relatively uncommon.

Level of Evidence: 

Therapeutic Level IV. See Instructions to Authors for a complete description of levels of evidence.

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    References

    Accreditation Statement
    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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    Joaquin Sanchez-Sotelo, MD, PhD
    Posted on October 07, 2010
    Dr. Sanchez-Sotelo responds to Dr. Green
    Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota

    Thank you very much for your recent letter regarding our paper “Failure Patterns After Linked Semiconstrained Total Elbow Arthroplasty for Posttraumatic Arthritis“ (2010;92:1432-41). As you rightly point out, there is a discrepancy between the 1997 paper from our institution and our more recent paper regarding the antibiotic mixed with polymethylmethacrylate at the time of component implantation.

    In the early Mayo experience, tobramycin was mixed with polymethylmethacrilate in order to decrease the rate of postoperative deep infection. The senior author switched to vancomycin around the year 2003. Reasons for the change included (1) awareness of the common role of gram- positive microorganisms in deep periprosthetic elbow infection, (2) good elution properties, and (3) cost.

    As mentioned by Dr. Green, deep periprosthetic infections continue to represent one of the most common failure modes for elbow arthroplasty. Currently, we continue to use antibiotic-loaded cement in every single primary or revision elbow arthroplasty performed at our institution. In the absence of prior elbow infection, vancomycin is our antibiotic of choice. In patients with a history of previous infection, a different antibiotic is selected based on susceptibility studies when available.

    We would like to thank Dr. Green for his observation and the Journal of Bone and Joint Surgery for allowing us to clarify our practice regarding the use of antibiotic-loaded cement.

    Andrew Green, MD
    Posted on August 25, 2010
    Antibiotic-Impregnated Cement in Total Elbow Arthroplasty for Posttraumatic Arthritis
    Warren Alpert Medical School, Brown University, Providence, Rhode Island

    To the Editor:

    In the article, "Failure Patterns After Linked Semiconstrained Total Elbow Arthroplasty for Posttraumatic Arthritis" (2010;92:1432-41), by Throckmorton et al., the authors indicate that as of 1983 they inserted the Coonrad/Morrey device with cement that was mixed with Vancomycin. In Schneeberger et al. (1) also from the Mayo Clinic the authors reported using Tobramycin impregnated cement from 1983 on. As these authors probably have the world's largest experience with this subject, I believe it would be appropriate for them to clarify this issue and report their current practice as well as the rationale for any changes during the course of their experience. As infection is the most common early complication, the authors' commentary on the use of antibiotic impregnated cement is important.

    The author did not receive any outside funding or grants in support of his research for or preparation of this work. The author, or a member of his immediate family, received, in any one year, payments or other benefits in excess of $10,000 or a commitment or agreement to provide such benefits from a commercial entity (Tornier, Inc.).

    Reference

    1. Schneeberger AG, Adams R, Morrey BF. Semiconstrained total elbow replacement for the treatment of post-traumatic osteoarthrosis. J Bone Joint Surg Am. 1997;79:1211-22.

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