1. Pathological fracture in cases of osteomyelitis of the shafts of long bones has occurred in one and two-thirds per cent. of a total of 1086 cases. Osteomyelitis has been responsible in this clinic for thirty-three and one-third per cent. of all pathological fractures in long bones.
2. Correct diagnosis and proper treatment at the earliest stage of the disease is obviously the most important prophylactic measure.
3. Every case with massive sequestration must be regarded as a fracture before abnormal mobility or deformity is evident.
4. A deep gutter rather than a shallow saucer is a safer mechanical means of dealing with central bone abscesses. In the removal of sequestra the involucrum should be conserved.
5. Careful attention should be paid to the proper provision of splints or other support during convalescence.