Fracture Repair: Challenges and Opportunities
Cato T. Laurencin, MD, PhD; Thomas A. Einhorn, MD; Karen Lyons, PhD

For twenty years, through their participation in a yearly symposium, the American Academy of Orthopaedic Surgeons (AAOS) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) at the National Institutes of Health (NIH) have worked collaboratively to comprehensively examine important scientific questions that face our profession. On April 25 through 28, 2007, leaders came together for the 2007 AAOS “Fracture Repair: Challenges and Opportunities” research symposium. In this twentieth symposium, prominent thought leaders—clinicians, scientists, and clinician scientists—assembled to discuss questions, come to consensus conclusions, and present a research agenda for the future.

The goal of the symposium was to define knowledge gaps in the area of fracture-healing, to describe and evaluate the use of new therapies for fracture repair, to examine successful models for translational research, and to study ways to optimize functional and clinical outcomes in fracture treatment now and in the future. Plenary lectures were delivered by the participants, followed by open periods of time for discussion and exchange. Breakout sessions were designed to further explore the issues that had been brought forth in the lectures and to arrive at consensus decisions …

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