RT Journal A1 Boyaci, Bilal A1 Hornicek, Francis A1 Rosenthal, Daniel A1 Mankin, Henry A1Pedlow, Jr. ,Frank X. A1 Carrier, Charles A1 Harms, Jurgen A1 Rosenberg, Andrew A1 Schwab, Joseph T1 Sarcoidosis of the SpineA Report of Five Cases and a Review of the Literature JF The Journal of Bone & Joint Surgery JO The Journal of Bone & Joint Surgery YR 2012 FD April 4 VO 94 IS 7 SP e42 1 OP 5 DO 10.2106/JBJS.K.00062 UL http://dx.doi.org/10.2106/JBJS.K.00062 AB Sarcoidosis, also called Morbus Boeck disease, is a potentially systemic disease defined by noncaseating granulomatous inflammation of uncertain etiology1. The natural history of sarcoidosis is unpredictable as it can involve one or multiple organ systems and it can be progressive or resolve spontaneously. While sarcoidosis has been described as affecting most organ systems, the lungs are involved in >90% of cases2. Skeletal involvement is much less frequent; the prevalence has been reported to range from <1% to 13%2,3. The small bones of the hands and feet are most often involved, whereas spinal disease is rare4. Most patients with spinal sarcoidosis present with axial pain that resolves either on its own or after the administration of corticosteroids. However, pathologic fractures have been reported with associated neurologic sequelae5,6.