RT Journal A1 Pui, Christine M. A1 Jergesen, Harry E. T1 Femoral Involvement by Langerhans Cell Histiocytosis Following Total Hip ArthroplastyA Case Report JF The Journal of Bone & Joint Surgery JO The Journal of Bone & Joint Surgery YR 2011 FD September 7 VO 93 IS 17 SP e98 1 OP 6 DO 10.2106/JBJS.K.00020 UL http://dx.doi.org/10.2106/JBJS.K.00020 AB Langerhans cell histiocytosis (LCH), formerly called "eosinophilic granuloma," is a benign bone neoplasm that is rare in adults. It is a cellular lesion with histiocytes, plasma cells, small lymphocytes, neutrophils, giant cells, foam cells, and eosinophilic leukocytes1. The disease typically presents during childhood, with >90% of cases occurring between the ages of five and fifteen years. LCH typically presents as a lytic medullary lesion with sharply defined margins, most commonly in the skull and in the diaphyses of long bones. The pelvis is affected in 5% to 17% of reported cases2,3.