RT Journal A1 Ries, Michael D. A1 Link, Thomas M. T1 Monitoring and Risk of Progression of Osteolysis After Total Hip Arthroplasty JF The Journal of Bone & Joint Surgery JO The Journal of Bone & Joint Surgery YR 2012 FD November 21 VO 94 IS 22 SP 2097 OP 2105 DO UL http://dx.doi.org/ AB Osteolytic lesions may develop after total hip arthroplasty from a biologic reaction to particulate debris. Loss of bone results from osteoclastic resorption and can be seen on radiographs as cystic lesions or radiolucent regions in proximity to the femoral and acetabular components. Osteolysis may be associated with pain, particularly if bone loss results in decreased mechanical support for the prosthetic components and implant loosening. However, osteolysis may also be asymptomatic and only detected with radiographic or other imaging modalities.