RT Journal A1 Sharma, Rajrishi A1 Vannabouathong, Christopher A1 Bains, Simrit A1 Marshall, Amanda A1 MacDonald, Steven J. A1 Parvizi, Javad A1 Bhandari, Mohit T1 Meta-Analyses in Joint Arthroplasty: A Review of Quantity, Quality, and Impact JF The Journal of Bone & Joint Surgery JO The Journal of Bone & Joint Surgery YR 2011 FD December 21 VO 93 IS 24 SP 2304 OP 2309 DO 10.2106/JBJS.J.01289 UL http://dx.doi.org/10.2106/JBJS.J.01289 AB A meta-analysis is a comprehensive systematic review in which statistical analyses are used to combine the results of two or more homogeneous clinical trials1-4. In the paradigm of evidence-based orthopaedics, meta-analysis can be an invaluable tool to increase study power and improve precision when study results are combined appropriately5. Evidence from a meta-analysis, however, is highly dependent on the quality of the primary studies included and on the overall methodological rigor6. Meta-analyses have impacted clinical practice, paved the way for clinical practice guidelines and health policies, and guided subsequent research6,7.