RT Journal A1 Pinzur, Michael S. T1 Levin and O’Neal’s The Diabetic Foot. 6th ed. JF The Journal of Bone & Joint Surgery JO The Journal of Bone & Joint Surgery YR 2001 FD April 1 VO 83 IS 4 SP 639 OP d DO UL http://dx.doi.org/ AB At any point in time, 3% to 4% of the diabetic population will have a foot ulcer, and 15% of the 16 million Americans with diabetes will have a foot ulcer in their lifetime. Following the development of a foot ulcer or infection, the risk of lower-extremity amputation is increased by a factor of eight, leading to over 50,000 such amputations yearly in the United States alone. No other disease affects as many organ systems and requires the interaction of as many medical disciplines. As knowledge has become available, each medical and surgical discipline has developed different strategies for tackling this health-care epidemic, but there has been very little interdisciplinary interaction.