RT Journal A1 Georgiades, George A1 Babis, George C. A1 Hartofilakidis, George T1 Charnley Low-Friction Arthroplasty in Young Patients with OsteoarthritisOutcomes at a Minimum of Twenty-two Years JF The Journal of Bone & Joint Surgery JO The Journal of Bone & Joint Surgery YR 2009 FD December 1 VO 91 IS 12 SP 2846 OP 2851 DO 10.2106/JBJS.H.00018 UL http://dx.doi.org/10.2106/JBJS.H.00018 AB Background: We previously reported the outcomes at a minimum of twelve years after eighty-four Charnley low-friction arthroplasties performed in patients with osteoarthritis who were less than fifty-six years old at the time of the surgery. We now update the results of that cohort at a minimum of twenty-two years postoperatively.Methods: Eighty-four hips (in sixty-nine patients) with osteoarthritis, which was secondary to congenital hip disease in sixty-four (76%) of them, were followed prospectively with use of the Merle D'Aubigné and Postel scoring system as modified by Charnley and with serial radiographs.Results: At the time of the latest follow-up, thirty-seven hips (44%) had failed. Twenty-eight acetabular and thirty femoral components, in a total of thirty-two hips, had been revised because of aseptic loosening; six of the loose femoral components were broken. Three hips were infected and were converted to a resection arthroplasty. A periprosthetic femoral fracture occurred in two additional hips, three and ten years postoperatively, and both were treated with internal fixation. Thirty-seven original acetabular components and thirty-six original femoral components were in place for an average of twenty-nine years. The probability of survival for both components, with failure for any reason as the end point, was 0.51 (95% confidence interval, 0.39 to 0.62) at twenty-five years.Conclusions: These long-term results can be used as a benchmark with which to compare outcomes of different designs when total hip arthroplasty is performed in young patients when the majority have congenital hip disease.Level of Evidence: Therapeutic Level IV. See Instructions to Authors for a complete description of levels of evidence.