RT Journal
A1 Okubadejo, Gbolahan
A1 Riew, K. Daniel
T1 Perils of Intravascular Methylprednisolone Injection into the Vertebral Artery
JF The Journal of Bone & Joint Surgery
JO The Journal of Bone & Joint Surgery
YR 2009
FD May 1
VO 91
IS 5
SP 1278
OP 1278
DO 
UL http://dx.doi.org/
AB 
Drs. Wainger and Rathmell raise the question of whether the findings of this study can be extrapolated to make long-term prognoses. Our animals were kept on ventilator support for only four to six hours after the insult to the brain, with none of the four animals in the methylprednisolone group being able to maintain appropriate oxygenation without ventilator support. No formal neurological examination could be performed on these obtunded animals. They were killed after the four to six-hour recovery period, which was deemed to be appropriate for postoperative recovery. In marked contrast, all animals in the nonparticulate group were able to walk and appeared completely normal.