RT Journal
A1 Bickels, Jacob
A1 Dadia, Shlomo
A1 Lidar, Zvi
T1 Surgical Management of Metastatic Bone Disease
JF The Journal of Bone & Joint Surgery
JO The Journal of Bone & Joint Surgery
YR 2009
FD June 1
VO 91
IS 6
SP 1503
OP 1516
DO 10.2106/JBJS.H.00175
UL http://dx.doi.org/10.2106/JBJS.H.00175
AB Metastatic bone disease is a major contributor to the deterioration of the quality of life of patients with cancer; it causes pain, impending and actual pathological fractures, and loss of function and may also be associated with considerable metabolic alterations.Operative treatment may be required for an impending or existing fracture and intractable pain. The goals of surgery are to provide local tumor control and allow immediate weight-bearing and function. Radiation therapy is often indicated postoperatively.Detailed preoperative evaluation is required to assess the local extent of bone destruction and soft-tissue involvement, involvement of other skeletal sites, and the overall medical and oncological status.