RT Journal
A1 Bhandari, Mohit
A1 Morshed, Saam
A1 TornettaIII, Paul
A1 Schemitsch, Emil H.
T1 Design, Conduct, and Interpretation of Nonrandomized Orthopaedic Studies: A Practical Approach(All) Evidence Matters
JF The Journal of Bone & Joint Surgery
JO The Journal of Bone & Joint Surgery
YR 2009
FD May 1
VO 91
IS Supplement_3
SP 1
OP 1
DO 10.2106/JBJS.H.01747
UL http://dx.doi.org/10.2106/JBJS.H.01747
AB 
The most sophisticated practice of evidence-based orthopaedics requires a clear delineation of relevant clinical questions, a thorough search of the literature relating to the questions, a critical appraisal of available evidence and its applicability to the clinical situation, and a balanced application of the conclusions to the clinical problem. The balanced application of the evidence (i.e., clinical decision-making) is the central point of practicing evidence-based medicine and involves an integration of our clinical expertise and judgment with patients' and societal values and with the best available research evidence.