RT Journal
A1 de Graaff, Esther
A1 Kozin, Scott H.
T1 Genetics of Radial Deficiencies
JF The Journal of Bone & Joint Surgery
JO The Journal of Bone & Joint Surgery
YR 2009
FD July 1
VO 91
IS Supplement_4
SP 81
OP 86
DO 10.2106/JBJS.I.00073
UL http://dx.doi.org/10.2106/JBJS.I.00073
AB 
More than 15% of the anomalies described in the London Dysmorphology Database are associated with various manifestations of radial longitudinal deficiency1. Their etiology may be genetic, environmental, or a combination of these factors. While most of the known inherited disorders are single-gene disorders, family members carrying the same mutation often show a range of phenotypes. This indicates that other genes and/or the environment play a large role in the phenotypic variability of radial longitudinal deficiency.